What Gives Oregano Its Power?

Oregano contains two chemically different groups of natural compounds, depending on whether we look at its extracts or its essential oil. Alcoholic and hydroalcoholic extracts of Origanum vulgare are particularly rich in polyphenols. The most important is rosmarinic...

Can a Herb Change How Your Medicines Work?

Yes – and St. John’s wort is one of the clearest examples. Many people assume that interactions occur only when two conventional medicines are taken together. But herbal preparations contain biologically active compounds too, and some can alter the way medicines...

St. John’s Wort: Effective, but Not Simple

St. John’s wort is unusual among medicinal herbs because it combines a relatively strong clinical evidence base with very important safety considerations. Standardized extracts have substantial clinical evidence for mild to moderate depression. However, St. John’s...

Where Does St. John’s Wort Have the Strongest Evidence?

St. John’s wort is one of the most extensively studied medicinal plants in modern phytotherapy. Its strongest clinical evidence concerns mild to moderate depression. Numerous randomized controlled trials and analyses combining results from multiple studies have...

What Gives St. John’s Wort Its Power?

St. John’s wort contains several groups of natural compounds, but two are particularly important for understanding its medicinal effects: hyperforin and hypericin-related compounds. Alcoholic and hydroalcoholic extracts of Hypericum perforatum contain hyperforin,...